Name of the Product
USP Pharmacopeial Impurities
Structure
(R)-(3-methyl-1-(pyrazine-2-
carboxamido)butyl)boronic acid
Bortezomib desphenylalanyl analog
N-(1-amino-1-oxo-3-phenylpropan-2-yl)
pyrazine-2-carboxamide
Bortezomib amide analog
(S)-3-phenyl-2-(pyrazine-2-carboxamido)
propanoic acid
Bortezomib acid analog
(S)-N-(1-formamido-1-oxo-3-
phenylpropan-2-yl)pyrazine-2-
carboxamide
Bortezomib N-formyl analog
((R)-3-methyl-1-((R)-3-phenyl-2-
(pyrazine-2-carboxamido)propanamido)
butyl)boronic acid
Bortezomib diasteromer (R,R)
N-((S)-1-(((R)-1-hydroxy-3-
methylbutyl)amino)-1-oxo-3-phenylpropan
-2-yl)pyrazine-2-carboxamide
(S,R) Bortezomib
hydroxyisopenyl amide analog
N-((S)-1-(((S)-1-hydroxy-3
-methylbutyl)amino)-1-oxo-3
-phenylpropan-2-yl)pyrazine-2
-carboxamide
(S,S) Bortezomib
hydroxyisopenyl amide analog
N-((2S)-1-((1-hydroxy-3-methylbutyl)amino)
-1-oxo-3-phenylpropan-2-yl)pyrazine
-2-carboxamide
(S,R) Bortezomib hydroxyisopenyl
amide and (S,S) Bortezomib
hydroxyisopenyl amide
N-((S)-1-(((R)-1-hydroperoxy-3
-methylbutyl)amino)-1-oxo-3-phenylpropan
-2-yl)pyrazine-2-carboxamide
Bortezomib R-hydroperoxide
N-((S)-1-(((S)-1-hydroperoxy-3
-methylbutyl)amino)-1-oxo-3-phenylpropan
-2-yl)pyrazine-2-carboxamide
Bortezomib S-hydroperoxide
N-((2S)-1-((1-hydroperoxy-3-methylbutyl)
amino)-1-oxo-3-phenylpropan-2-yl)
pyrazine-2-carboxamide
Bortezomib R-hydroperoxide and
Bortezomib S-hydroperoxide
((R)-3-methyl-1-((S)-3-phenyl-2-((S)
-3-phenyl-2-(pyrazine-2-carboxamido)
propanamido)
propanamido)butyl)
boronic acid
Bortezomib L-phenylalanyl analog
((R)-3-methyl-1-((S)-3-phenyl-2-((R)
-3-phenyl-2-(pyrazine-2-carboxamido)
propanamido)
propanamido)butyl)
boronic acid
Bortezomib D-phenylalanyl
analog
(S)-N-(1-amino-1-oxo-3-phenylpropan-
2-yl)pyrazine-2-carboxamide
(R)-3-phenyl-2-(pyrazine-2-carboxamido)
propanoic acid
((S)-3-methyl-1-((R)-3-phenyl-2-
(pyrazine-2-carboxamido)propanamido)
butyl)boronic acid
Bortezomib diastereomer (S,R)
((S)-3-methyl-1-((S)-3-phenyl-2-
(pyrazine-2-carboxamido)propanamido)
butyl)boronic acid
Bortezomib diastereomer (S,S)
