Bendamustine Impurities




Name of the Product

USP Pharmacopeial impurities

Structure

4-(5-(Bis(2-hydroxyethyl)
amino)-1-methyl-1H-benzo[d]
imidazol-2-yl)butanoic acid

Bend-USP RC-A

Ethyl 4-(5-(bis(2-hydroxyethyl)
amino)-1-methyl-1H-benzo[d]
imidazol-2-yl)butanoate

Bend-USP RC-C

4-(5-((2-Chloroethyl)amino)
-1-methyl-1H-benzo[d]imidazol
-2-yl)butanoic acid

Bend-USP RC-D

Ethyl 4-(5-((2-chloroethyl)
(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]
imidazol-2-yl)butanoate

4-(5-((2-Chloroethyl)(2-hydroxyethyl)
amino)-1-methyl-1H-benzo[d]
imidazol-2-yl)butanoic acid

Bend-USP RC-E

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,
8-tetrahydroimidazo[4',5':5,6]
benzo[1,2-b][1,4]thiazin-2-yl)
butanoic acid

Bend-USP RC-G

Ethyl 4-(5-(bis(2-chloroethyl)
amino)-1-methyl-1H-benzo[d]
imidazol-2-yl)butanoate

Bend-USP RC-I